Information de reference pour ce titreAccession Number: | 00125357-200803000-00012.
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Author: | Rodriguez-Bano, J. 1; Marti, S. 2; Soto, S. 2; Fernandez-Cuenca, F. 3; Cisneros, J. M. 4; Pachon, J. 4; Pascual, A. 3; Martinez-Martinez, L. 5; McQueary, C. 6; Actis, L. A. 6; Vila, J. 2; the Spanish Group for the Study of Nosocomial Infections (GEIH)
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Institution: | (1)Seccion de Enfermedades Infecciosas, (3)Servicio de Microbiologia, Hospital Universitario Virgen Macarena, Sevilla, (2)Servicio de Microbiologia, Hospital Clinic, Barcelona, (4)Servicio de Enfermedades Infecciosas, Hospital Universitario Virgen del Rocio, Sevilla, (5)Servicio de Microbiologia, Hospital Universitario Marques de Valdecilla, Santander, Spain, (6)Department of Microbiology, Miami University, Oxford, OH, USA
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Title: | Biofilm formation in Acinetobacter baumannii: associated features and clinical implications.[Miscellaneous]
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Source: | Clinical Microbiology & Infection. 14(3):276-278, March 2008.
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Abstract: | Biofilm formation in 92 unrelated strains of Acinetobacter baumannii isolated in a multicentre cohort study was investigated using a microtitre plate assay. Fifty-six (63%) isolates formed biofilm. These isolates were less frequently resistant to imipenem or ciprofloxacin than were non-biofilm-forming isolates (25% vs. 47%, p 0.04; and 66% vs. 94%, p 0.004, respectively). All catheter-related urinary or bloodstream infections and the sole case of shunt-related meningitis were caused by biofilm-forming strains. Multivariate analysis revealed that treatment in an intensive care unit, ciprofloxacin resistance and isolation from a respiratory sample were associated with non-biofilm-forming isolates, while previous aminoglycoside use was associated with biofilm-forming isolates.
Copyright (C) 2008 Blackwell Publishing Ltd.
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Author Keywords: | Acinetobacter baumannii; biofilm formation; ciprofloxacin resistance; imipenem resistance; infections; risk-factors.
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Language: | English.
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Document Type: | RESEARCH NOTE.
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Journal Subset: | Clinical Medicine.
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ISSN: | 1198-743X
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NLM Journal Code: | dy9, 9516420
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