Information de reference pour ce titreAccession Number: | 00009017-200501001-00044.
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Author: | Hellekant, Goran 1,2; Danilova, Vicktoria 1
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Institution: | (1)Department of Animal Health and Biomedical Sciences, University of Wisconsin-Madison, 1656 Linden Drive, Madison WI 53706, USA (2)Department of Physiology and Pharmacology, University of Minnesota-Duluth, MN 55812, USA
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Title: | Brazzein a Small, Sweet Protein: Discovery and Physiological Overview.[Report]
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Source: | Chemical Senses. Proceedings of ISOT/JASTS 2004. 30 (Supplement 1):i88-i89, January 2005.
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Author Keywords: | brazzein; chorda tympani; high potency sweeteners; primates; structure-function; sweet taste.
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References: | Brouwer, J.N., van der Wel, H., Francke, A. and Henning, G.J. (1968) Miraculin, the sweetness-inducing protein from miracle fruit. Nature, 220, 373-374.
Caldwell, J.E., Abildgaard, F., Dzakula, Z., Ming, D., Hellekant, G. and Markley, J.L. (1998a) Solution structure of the thermostable sweet-tasting protein brazzein. Nat. Struct. Biol., 5, 427-431.
Caldwell, J.E., Abildgaard, F., Ming, D., Hellekant, G. and Markley, J.L. (1998b) Complete 1H and partial 13C resonance assignments at 37 and 22 degrees C for brazzein, an intensely sweet protein. J. Biomol. NMR, 11, 231-232.
Danilova, V., Danilov, Y., Roberts, T., Tinti, J.M., Nofre, C. and Hellekant, G. (2002) The sense of taste in a New World monkey, the common marmoset: recordings from the chorda tympani and glossopharyngeal nerves. J. Neurophysiol., 88, 579-594.
Faus, I. (2000) Recent developments in the characterization and biotechnological production of sweet-tasting proteins. Appl. Microbiol. Biotechnol., 53, 145-251.
Guan, Z., Hellekant, G. and Yan, W. (1995) Expression of sweet protein brazzein by Saccharomyces cerevisiae. Chem. Senses, 20, 701.
Hellekant, G., Danilova, V. and Ninomiya, Y. (1997a) Primate sense of taste: behavioral and single chorda tympani and glossopharyngeal nerve fiber recordings in the rhesus monkey, Macaca mulatta. J. Neurophysiol., 77, 978-993.
Hellekant, G., Ninomiya, Y. and Danilova, V. (1997b) Taste in chimpanzees II: single chorda tympani fibers. Physiol. Behav., 61, 829-841.
Hellekant, G., Ninomiya, Y. and Danilova, V. (1998) Taste in chimpanzees III: Labeled line coding in sweet taste. Physiol. Behav., 65, 191-200.
Hladik, C.M. and Hladik, A. (1988) Sucres et 'Faux Sucres' [QUOTES OK?] de la foret equatoriale: evolution et perception des produits sucres par les populations forestieres D'Afrique. J. Agric. Trad. Bota Appl., XXXV, 35-50.
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Inglett, G.E. (1974) Sweeteners: new challenges and concepts. In Inglett, G.E. (ed.), Symposium: Sweeteners. Avi, Westport, CT, Vol. 1, pp. 1-9.
Izawa, H., Ota, M., Kohmura, M. and Ariyoshi, Y. (1996) Synthesis and characterization of the sweet protein Brazzein. Biopolymers, 39, 95-101.
Jin, Z., Danilova, V., Assadi-Porter, F.M., Aceti, D.J., Markley, J.L. and Hellekant, G. (2003a) Critical regions for the sweetness of brazzein. FEBS Lett., 544, 33-37.
Jin, Z., Danilova, V., Assadi-Porter, F., Markley, J. and Hellekant, G. (2003b) Monkey electrophysiological and human psychophysical responses to mutants of the sweet protein brazzein: delineating brazzein sweetness. Chem. Senses, 28, 491-498.
Kurihara, K. and Beidler, L.M. (1968) Taste-modfying protein from miracle fruit. Science, 161, 1241-1243.
Ming, D. and Hellekant, G. (1994) Brazzein, a new high-potency thermostable sweet protein from Pentadiplandra brazzeana B. FEBS Lett., 355, 106-108.
Morris, J.A. and Cagan, R.H. (1972) Purification of monellin, the sweet principle of Dioscorephyllum cumminsii. Biochim. Biophys. Acta, 261, 114-122.
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van der Wel, H., Larson, G., Hellekant, G., Hladik, A., Hladik, C.M. and Glaser, D. (1989) Isolation and characterization of Pentadin, the sweet principle of Pentadiplandra brazzeiana Baillon. Chem. Senses, 14, 75-79.
Yamashita, H., Akabane, T. and Kurihara, Y. (1995). Activity and stability of a new sweet protein with taste-modifying action, curculin. Chem. Senses, 20, 239-243.
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Language: | English.
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Document Type: | II. Symposium session - Taste - T7. Structure-function relationship of sweet tastants and modifiers (organized by T. Imoto, K. Hanai and T. Tanimura).
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Journal Subset: | Clinical Medicine.
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ISSN: | 0379-864X
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NLM Journal Code: | b4b, 8217190
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