Information de reference pour ce titreAccession Number: | 00006056-200004060-00027.
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Author: | Velicer, Gregory J. *+; Kroos, Lee *; Lenski, Richard E. +
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Institution: | * Department of Biochemistry, Michigan State University, East Lansing, Michigan 48824, USA + Center for Microbial Ecology, Michigan State University, East Lansing, Michigan 48824, USA
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Title: | Developmental cheating in the social bacterium Myxococcus xanthus.[Letter]
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Source: | Nature. Insight: Obesity. 404(6778):598-601, April 6, 2000.
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Abstract: | Cheating is a potential problem in any social system that depends on cooperation and in which actions that benefit a group are costly to individuals that perform them 1-5. Genetic mutants that fail to perform a group-beneficial function but that reap the benefits of belonging to the group should have a within-group selective advantage, provided that the mutants are not too common. Here we show that social cheating exists even among prokaryotes. The bacterium Myxococcus xanthus exhibits several social behaviours, including aggregation of cells into spore-producing fruiting bodies during starvation. We examined a number of M. xanthus genotypes that were defective for fruiting-body development, including several lines that evolved for 1,000 generations under asocial conditions 6 and others carrying defined mutations in developmental pathways 7-10, to determine whether they behaved as cheaters when mixed with their developmentally proficient progenitor. Clones from several evolved lines and two defined mutants exhibited cheating during development, being over-represented among resulting spores relative to their initial frequency in the mixture. The ease of finding anti-social behaviours suggests that cheaters may be common in natural populations of M. xanthus.
(C) 2000 Nature Publishing Group
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References: | 1. Maynard Smith, J. Evolution and the Theory of Games (Cambridge Univ. Press, Cambridge, 1982).
2. Axelrod, R. M. The Evolution of Cooperation (Basic Books, New York, 1984).
3. Pellmyr, O., Leebens-Mack, J. & Huth, C. J. Non-mutualistic yucca moths and their evolutionary consequences. Nature 380, 155-156 (1996).
4. Matapurkar, A. K. & Watve, M. G. Altruist cheater dynamics in Dictyostelium: aggregated distribution gives stable oscillations. Am. Nat. 150, 790-797 (1997).
5. Frank, S. A. Foundations of Social Evolution (Princeton Univ. Press, Princeton, 1998).
6. Velicer, G. J., Kroos, L. & Lenski, R. E. Loss of social behaviors by Myxococcus xanthus during evolution in an unstructured habitat. Proc. Natl Acad. Sci. USA 95, 12376-12380 (1998).
7. Kuspa, A., Kroos, L. & Kaiser, D. Intercellular signaling is required for developmental gene expression in Myxococcus xanthus. Dev. Biol. 117, 267-276 (1986).
8. Shimkets, L. J. & Asher, S. J. Use of recombination techniques to examine the structure of the csg locus of Myxococcus xanthus. Mol. Gen. Genet. 211, 63-71 (1988).
9. Kuspa, A. & Kaiser, D. Genes required for developmental signaling in Myxococcus xanthus: three asg loci. J. Bacteriol. 171, 2762-2772 (1989).
10. Garza, A. G., Harris, B. Z., Pollack, J. S., Tzeng, L. & Singer, M. The asgE locus is required for cell-cell signaling during Myxococcus xanthus development. Mol. Microbiol. 35, 812-824 (2000).
11. Bonner, J. T. The Cellular Slime Molds (Princeton Univ. Press, Princeton, 1967).
12. Kaiser, D. Control of multicellular development: Dictyostelium and Myxococcus. Annu. Rev. Genet. 20, 539-566 (1986).
13. Reichenbach, H. in Myxobacteria II (eds Dworkin, M. & Kaiser, D.) 13-62 (Am. Soc. Microbiol., Washington, DC, 1993).
14. Dworkin, M. & Kaiser, D. (eds) Myxobacteria II (Am. Soc. Microbiol., Washington, DC, 1993).
15. Rosenberg, E. & Varon, M. in Myxobacteria: Development and Cell Interactions (ed. Rosenberg, E.) 109-125 (Springer, New York, 1984).
16. Kaiser, D. Social gliding is correlated with the presence of pili in Myxococcus xanthus. Proc. Natl Acad. Sci. USA 76, 5952-5956 (1979).
17. Hagen, D. C., Bretscher, A. P. & Kaiser, D. Synergism between morphogenetic mutants of Myxococcus xanthus. Dev. Biol. 64, 284-296 (1978).
18. Downard, J., Ramaswamy, S. V. & Kil, K. Identification of esg, a genetic locus involved in cell-cell signaling during Myxococcus xanthus development. J. Bacteriol. 175, 7762-7770 (1993).
19. Laue, B. E. & Gill, R. E. Using a phase-locked mutant of Myxococcus xanthus to study the role of phase variation in development. J. Bacteriol. 177, 4089-4096 (1995).
20. Buss, L. W. Somatic cell parasitism and the evolution of somatic tissue compatibility. Proc. Natl Acad. Sci. USA 79, 5337-5341 (1982).
21. Nowak, M. A. & May, R. M. Evolutionary games and spatial chaos. Nature 359, 826-829 (1992).
22. Frank, S. A. Mutual policing and repression of competition in the evolution of cooperative groups. Nature 377, 520-522 (1995).
23. Maynard Smith, J. & Szathmary, E. The Major Transitions in Evolution (Oxford Univ. Press, New York, 1995).
24. Grosberg, R. K. & Strathmann, R. R. One cell, two cell, red cell, blue cell: the persistence of a unicellular stage in multicellular life histories. Trends Ecol. Evol. 13, 112-116 (1998).
25. Buss, L. W. Slime molds, ascidians, and the utility of evolutionary theory. Proc. Natl Acad. Sci. USA 96, 8801-8803 (1999).
26. Stoner, D. S., Rinkevich, B. & Weissman, I. L. Heritable germ and somatic cell lineage competitions in chimeric colonial protochordates. Proc. Natl Acad. Sci. USA 96, 9148-9153 (1999).
27. Turner, P. E. & Chao, L. Prisoner's dilemma in an RNA virus. Nature 398, 441-443 (1999).
28. Hodgkin, J. & Kaiser, D. Cell-to-cell stimulation of motility in nonmotile mutants of M. xanthus. Proc. Natl Acad. Sci. USA 74, 2938-2942 (1977).
29. Wall, D., Kolenbrander, P. E. & Kaiser, D. The Myxococcus xanthus pilQ (sglA) gene encodes a secretin homolog required for type IV pilus biogenesis, social motility and development. J. Bacteriol. 181, 24-33 (1999).
30. Kroos, L., Kuspa, A. & Kaiser, D. A global analysis of developmentally regulated genes in Myxococcus xanthus. Dev. Biol. 117, 252-266 (1986).
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Language: | English.
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Document Type: | Letters to Nature.
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Journal Subset: | Life Sciences. Physical Science & Engineering.
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ISSN: | 0028-0836
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NLM Journal Code: | 0410462, nsc
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