An Aboriginal Australian Genome Reveals Separate Human Dispersals into Asia.
Rasmussen, Morten 1,2,*; Guo, Xiaosen 2,3,*; Wang, Yong 4,*; Lohmueller, Kirk E. 4,*; Rasmussen, Simon 5; Albrechtsen, Anders 6; Skotte, Line 6; Lindgreen, Stinus 1,6; Metspalu, Mait 7; Jombart, Thibaut 8; Kivisild, Toomas 9; Zhai, Weiwei 10; Eriksson, Anders 11; Manica, Andrea 11; Orlando, Ludovic 1; De La Vega, Francisco M. 12; Tridico, Silvana 13; Metspalu, Ene 7; Nielsen, Kasper 5; Avila-Arcos, Maria C. 1; Moreno-Mayar, Victor J. 1,14; Muller, Craig 15; Dortch, Joe 16; Gilbert, Thomas M. P. 1,2; Lund, Ole 5; Wesolowska, Agata 5; Karmin, Monika 7; Weinert, Lucy A. 8; Wang, Bo 3; Li, Jun 3; Tai, Shuaishuai 3; Xiao, Fei 3; Hanihara, Tsunehiko 17; Driem, George van 18; Jha, Aashish R. 19; Ricaut, Francois-Xavier 20; de Knijff, Peter 21; Migliano, Andrea B 9,22; Romero, Irene Gallego 19; Kristiansen, Karsten 2,3,6; Lambert, David M. 23; Brunak, Soren 5,24; Forster, Peter 25,26; Brinkmann, Bernd 26; Nehlich, Olaf 27; Bunce, Michael 13; Richards, Michael 27,28; Gupta, Ramneek 5; Bustamante, Carlos D. 12; Krogh, Anders 1,6; Foley, Robert A. 9; Lahr, Marta M. 9; Balloux, Francois 8; Sicheritz-Ponten, Thomas 5,29; Villems, Richard 7,30; Nielsen, Rasmus 4,6,+; Wang, Jun 2,3,6,31,+; Willerslev, Eske 1,2,+
[Report]
Science.
334(6052):94-98, October 7, 2011.
(Format: HTML, PDF)
: We present an Aboriginal Australian genomic sequence obtained from a 100-year-old lock of hair donated by an Aboriginal man from southern Western Australia in the early 20th century. We detect no evidence of European admixture and estimate contamination levels to be below 0.5%. We show that Aboriginal Australians are descendants of an early human dispersal into eastern Asia, possibly 62,000 to 75,000 years ago. This dispersal is separate from the one that gave rise to modern Asians 25,000 to 38,000 years ago. We also find evidence of gene flow between populations of the two dispersal waves prior to the divergence of Native Americans from modern Asian ancestors. Our findings support the hypothesis that present-day Aboriginal Australians descend from the earliest humans to occupy Australia, likely representing one of the oldest continuous populations outside Africa.
Copyright (C) 2011 by the American Association for the Advancement of Science
Ovid
®
